CORE OUTCOME PROJECTS
The aim of IMPROVED is to develop core outcome sets for skin diseases and conditions that can be treated by pharmacologic as well as non-pharmacologic interventions, particularly procedures or surgery. Each outcome set is a separate project and is based on the CSG-COUSIN roadmap, as well as methodologic guidance put forth by COMET.
Rosacea is a common condition affecting the facial skin and eyes. Treatments include medications, behavioral changes, and non-pharmacologic interventions, such as lasers and light sources.
The etiology of rosacea remains poorly understood, slowing the development of effective treatments. Additionally, the absence of a core outcome set for rosacea complicates efforts to compare results of the clinical trials that have been performed. A core outcome set for treatment of rosacea may help uncover the relative benefits and harms of different treatment modalities as well as facilitate dose selection within modalities.