CORE OUTCOME PROJECTS

The aim of IMPROVED is to sequentially develop core outcome sets of relevance to skin diseases and conditions that can be treated by pharmacologic as well as non-pharmacologic interventions.   Each outcome set is an entirely separate project and is based on the CSG-COUSIN roadmap, as well as methodologic guidance put forth by COMET.

POST-INFLAMMATORY HYPERPIGMENTATION

Many randomized controlled trials in dermatology, plastic surgery, otolaryngology, ophthalmology, and other fields investigate interventions to improve the visible signs of aging, both photoaging and chronological aging.  Interventions to address the appearance of aged skin and subcutis include surgery as well as minimally invasive techniques like injectables, lasers and energy devices.

While aging is not a disease, its physical manifestations constitute a treatable condition, for which a core outcome set can be developed.  Participants in this core outcome set include international, multidisciplinary team designed to ensure that the resulting set is applicable across specialties and for a range of potential interventions.